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  • Photo: Smita Iyer

    Smita Iyer- PhD
    Assistant Professor and Assistant Professor in Residence
    Center for Comparative Medicine
    Pathology, Microbiology & Immunology


    smiyer@ucdavis.edu

       

    Active Research Grants

    Principal Investigator, Targeting CD4 TFH cells to enhance HIV vaccine-induced humoral immunity , (Principal Investigator), NIAID, NIH

    Principal Investigator, Role of vaginal microbiome and metabolome on HIV vaccine efficacy, (Principal Investigator), NATIONAL INSTITUTES OF HEALTH

    Most Recent 10 Publications

    • Smita Iyer: Dynamics of SIV-specific CXCR5+ CD8 T cells during chronic SIV infection 2017 Mylvaganam GH, Rios D, Abdelaal HM, Iyer S, Tharp G, Mavinger M, Hicks S, Chahroudi A, Ahmed R, Bosinger SE, Williams IR, Skinner PJ, Velu V, Amara RR Dynamics of SIV-specific CXCR5+ CD8 T cells during chronic SIV infection Proc Natl Acad Sci USA,
    • Smita Iyer: Loss of Junctional Adhesion
Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat,
Fructose, and Cholesterol 2016 Rahman K, Desai C, Iyer SS, Thorn NE, Kumar P, Liu Y, Smith T, Neish AS, Li H, Tan S, Wu P, Liu X, Farris AB, Nusrat A, Parkos C, Anania F Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol Gastroenterology,
    • Smita Iyer: Virus-like particles displaying trimeric SIV envelope gp160
enhance the breadth of DNA/MVA SIV vaccine induced antibody responses in rhesus
macaques 2016 Iyer SS, Gangadhara S, Victor B, Shen Xiaoying, Chen Xuemin, Kasturi S, Sabula M, Labranche C, Reddy P, Tomaras G, Montefiori D, Moss B, Spearman P, Pulendran B, Kozlowski P and Amara R. Virus-like particles displaying trimeric SIV envelope gp160 enhance the breadth of DNA/MVA SIV vaccine induced antibody responses in rhesus macaques J Virol,
    • Smita Iyer:  Induction of TH1-biased T Follicular helper cells in lymphoid tissue
during chronic simian immunodeficiency virus infection defines functionally distinct germinal
center TFH cells 2016 Velu V, Mylvaganam GH, Gangadhara S, Hong JJ, Iyer SS, Gumber S, Ibegbu C, Villinger G, Amara R Induction of TH1-biased T Follicular helper cells in lymphoid tissue during chronic simian immunodeficiency virus infection defines functionally distinct germinal center TFH cells J Immunol,
    • Smita Iyer: Codelivery of Envelope Protein in Alum with MVA
Vaccine Induces CXCR3-Biased CXCR5+ and CXCR5- CD4 T Cell Responses in Rhesus
Macaques 2015 Iyer SS, Gangadhara S, Victor B, Gomez R, Basu R, Hong JJ, Labranche C, Montefiori DC, Villinger F, Moss B, Amara RR Codelivery of Envelope Protein in Alum with MVA Vaccine Induces CXCR3-Biased CXCR5+ and CXCR5- CD4 T Cell Responses in Rhesus Macaques J Immunol,
    • Smita Iyer: CD40L-Adjuvanted DNA/MVA SIV Vaccine Enhances Protection Against Neutralization
Resistant Mucosal SIV Infection 2015 Kwa S, Sadagopal S, Shen X, Hong JJ, Gangadhara S, Basu R, Victor B, Iyer SS, LaBranche CC, Montefiori DC, Tomaras GD, Villinger F, Moss B, Kozlowski PA, Amara RR CD40L-Adjuvanted DNA/MVA SIV Vaccine Enhances Protection Against Neutralization Resistant Mucosal SIV Infection J Virol,
    • Smita Iyer: Costimulatory molecules as vaccine adjuvants: to 4-1BB or not to 4-1BB? 2014 Rahman K, Iyer SS Costimulatory molecules as vaccine adjuvants: to 4-1BB or not to 4-1BB? Cell Mol Immunol,
    • Smita Iyer: DNA/MVA Vaccines for HIV/AIDS 2014 Iyer SS, Amara RR DNA/MVA Vaccines for HIV/AIDS Vaccines,
    • Smita Iyer: Interplay
between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during
chronic LCMV infection 2014 Penaloza-MacMaster P, Kamphorst A, Wieland A, Araki K, Iyer SS, West EE, Mara L, Yang S, Konieczny BT, Sharpe AH, Freeman GJ, Rudensky AY, Ahmed R Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection J Exp Med,
    • Smita Iyer: Identification of novel markers for mouse CD4+ T follicular helper cells 2013 Iyer SS, Latner DR, Zilliox MJ, McCausland M, Akondy RS, Macmaster-Penaloza P, Hale JS, Ye L, Mohammed AU, Yamaguchi T, Sakaguchi S, Amara RR, Ahmed R Identification of novel markers for mouse CD4+ T follicular helper cells EJI,

    Most Recent 5 Book Chapters

    2010 Rojas M, Iyer S, Co C, Brigham K: Animal models of Lung Injury: Role for Mesenchymal Stem Cells. Stem Cells in the Respiratory System, Krisnarao Appasani, Raghu K. Appansani, (ed), Stem Cell Biology and Regenerative Medicine. 141-158.