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  • Photo: Melanie Gareau

    Melanie Gareau
    Assistant Adjunct Professor and Researcher
    Anatomy, Physiology & Cell Biology


    mgareau@ucdavis.edu

       

    Education

    2011 Microbiology, The Hospital for Sick Children, Toronto, Ontario, Canada
    2006 PhD Physiology, McMaster University, Hamilton, Ontario, Canada
    2001 BS Biochemistry, Pharmacology, McGill University, Montreal, Quebec, Canada

    Honors and Awards

    2011 FASEB Summer Research Conference travel award
    2010 Journal of Biochemistry poster prize, Experimental Biology
    2009-2011 Reva Gerstein Graduate Fellowship in Paediatric Psychology Fund, Hospital for Sick Children Research Institute (2yrs)
    2009 VTEC2009 Dr. Carlos Gianantonio Award travel award
    2009 Experimental Biology, APS Takeda travel award
    2008 ASM Beneficial Microbes travel award
    2008 University of Toronto, Department of Medicine, Gastroenterology Research Day Poster prize
    2007-2010 Canadian Institutes of Health Research/Crohn’s and Colitis Foundation of Canada/Institut Rosell Fellowship, (3 yrs)
    2007-2009 Canadian Institutes of Health Research/Canadian Association of Gastroenterology/Crohn’s and Colitis Foundation of Canada Fellowship, (2 yrs)
    2006 Restracomp Post-doctoral Fellowship, Hospital for Sick Children
    2006 Institut Rosell Probiotic Challenge Poster competition
    2005 Crohn's and Colitis Foundation of America travel award
    2005 Johnson and Johnson summer internship, $15,000
    2005 Ontario Graduate Scholarship in Science and Technology doctoral award
    2004 Crohn's and Colitis Foundation of Canada student prize

    Active Research Grants

    Principal Investigator, The role of the microbiota-gut-brain axis in IBD, (Principal Investigator), Crohn’s & Colitis Foundation of America (CCFA) Career Development Award

    Principal Investigator, The Developing Microbiota-Gut-Brain axis, (Principal Investigator), NIH

    Principal Investigator, Early Microbial Colonization and Development of the Microbiota-Gut-Brain axis, (Principal Investigator), UC Davis MIND Institute

    Principal Investigator, GI pathophysiology following early life environmental exposure, (Principal Investigator), EHS NIEHS program project pilot grant

    Principal Investigator, EHS scholar, (Principal Investigator), NIEHS P30

    Most Recent 10 Publications

    • Melanie Gareau: TRPM8 on mucosal sensory nerves regulates colitogenic responses by innate immune cells via CGRP 2015 de Jong PR, Takahashi N, Peiris M, Bertin S, Lee J, Gareau MG, Paniagua A, Harris AR, Herdman DS, Corr M, Blackshaw LA, Raz E TRPM8 on mucosal sensory nerves regulates colitogenic responses by innate immune cells via CGRP Mucosal Immunol,
    • Melanie Gareau: High fat diet causes depletion of intestinal eosinophils associated with intestinal permeability. 2015 Johnson AM, Costanzo A, Gareau MG, Armando AM, Quehenberger O, Jameson JM, Olefsky JM High fat diet causes depletion of intestinal eosinophils associated with intestinal permeability. PloS one,
    • Melanie Gareau: Salmonella-induced Diarrhea Occurs in the Absence of IL-8 Receptor (CXCR2)-Dependent Neutrophilic Inflammation. 2015 Marchelletta RR, Gareau MG, Okamoto S, Guiney DG, Barrett KE, Fierer J Salmonella-induced Diarrhea Occurs in the Absence of IL-8 Receptor (CXCR2)-Dependent Neutrophilic Inflammation. J Infect Dis,
    • Melanie Gareau: Probiotics normalize the gut-brain-microbiota axis in immunodeficient mice 2014 Smith CJ, Emge JR, Berzins K, Lung L, Khamishon R, Shah P, Rodrigues DM, Sousa AJ, Reardon C, Sherman PM, Barrett KE, Gareau MG Probiotics normalize the gut-brain-microbiota axis in immunodeficient mice Am J Physiol Gastrointest Liver Physiol,
    • Melanie Gareau: Fluid and electrolyte secretion in the inflamed gut: novel targets for treatment of inflammation-induced diarrhea 2013 Gareau MG, Barrett KE Fluid and electrolyte secretion in the inflamed gut: novel targets for treatment of inflammation-induced diarrhea Current Opinion in Pharmacology,
    • Melanie Gareau: TLR3, TRIF, and caspase 8 determine double-stranded RNA-induced epithelial cell death and survival in vivo 2013 McAllister CS, Lakhdari O, Pineton de Chambrun G, Gareau MG, Broquet A, Lee GH, Shenouda S, Eckmann L, Kagnoff MF TLR3, TRIF, and caspase 8 determine double-stranded RNA-induced epithelial cell death and survival in vivo Journal of Immunology (Baltimore, Md. : 1950),
    • Melanie Gareau: Altered expression and localization of ion transporters contribute to diarrhea in mice with Salmonella-induced enteritis 2013 Marchelletta RR, Gareau MG, McCole DF, Okamoto S, Roel E, Klinkenberg R, Guiney DG, Fierer J, Barrett KE Altered expression and localization of ion transporters contribute to diarrhea in mice with Salmonella-induced enteritis Gastroenterology,
    • Melanie Gareau: Rac2-deficiency leads to exacerbated and protracted colitis in response to Citrobacter rodentium infection 2013 Fattouh R, Guo CH, Lam GY, Gareau MG, Ngan BY, Glogauer M, Muise AM, Brumell JH Rac2-deficiency leads to exacerbated and protracted colitis in response to Citrobacter rodentium infection Public Library of Science ONE,
    • Melanie Gareau: Probiotics are effective for the prevention and treatment of Citrobacter rodentium-induced colitis in mice 2012 Rodrigues DM, Sousa AJ, Johnson-Henry KC, Sherman PM, Gareau MG Probiotics are effective for the prevention and treatment of Citrobacter rodentium-induced colitis in mice The Journal of Infectious Diseases,
    • Melanie Gareau: Matrix metalloproteinase 9 contributes to gut microbe homeostasis in a model of infectious colitis 2012 Rodrigues DM, Sousa AJ, Hawley SP, Vong L, Gareau MG, Kumar SA, Johnson-Henry KC, Sherman PM Matrix metalloproteinase 9 contributes to gut microbe homeostasis in a model of infectious colitis BMC Microbiology,

    Most Recent 5 Book Chapters

    2014 Gareau MG: Microbiota-gut-brain axis and cognitive function, , Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease. 357-371.

    External Links

    Lab Website