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  • Photo: Melanie Gareau

    Melanie Gareau
    Assistant Professor and Assistant Professor in Residence
    Anatomy, Physiology & Cell Biology


    mgareau@ucdavis.edu

       

    Education

    2011 Microbiology, The Hospital for Sick Children, Toronto, Ontario, Canada
    2006 PhD Physiology, McMaster University, Hamilton, Ontario, Canada
    2001 BS Biochemistry, Pharmacology, McGill University, Montreal, Quebec, Canada

    Honors and Awards

    2011 FASEB Summer Research Conference travel award
    2010 Journal of Biochemistry poster prize, Experimental Biology
    2009-2011 Reva Gerstein Graduate Fellowship in Paediatric Psychology Fund, Hospital for Sick Children Research Institute (2yrs)
    2009 VTEC2009 Dr. Carlos Gianantonio Award travel award
    2009 Experimental Biology, APS Takeda travel award
    2008 ASM Beneficial Microbes travel award
    2008 University of Toronto, Department of Medicine, Gastroenterology Research Day Poster prize
    2007-2010 Canadian Institutes of Health Research/Crohn’s and Colitis Foundation of Canada/Institut Rosell Fellowship, (3 yrs)
    2007-2009 Canadian Institutes of Health Research/Canadian Association of Gastroenterology/Crohn’s and Colitis Foundation of Canada Fellowship, (2 yrs)
    2006 Restracomp Post-doctoral Fellowship, Hospital for Sick Children
    2006 Institut Rosell Probiotic Challenge Poster competition
    2005 Crohn's and Colitis Foundation of America travel award
    2005 Johnson and Johnson summer internship, $15,000
    2005 Ontario Graduate Scholarship in Science and Technology doctoral award
    2004 Crohn's and Colitis Foundation of Canada student prize

    Active Research Grants

    Principal Investigator, Probiotics and the Microbiota Gut Brain Axis, (Principal Investigator), NIH-NCCIH

    Co-Investigator, Cholecystokinin - Role In Postprandial Gastric Motility, Helen Raybould (Principal Investigator), NIH

    Principal Investigator, The microbiota-gut-brain axis in pediatric IBD, (Principal Investigator), Crohn's and Colitis Foundation of America

    Co-Principal Investigator, Synergy between milk and probiotic bacteria for gastrointestinal health, Maria Marco (Principal Investigator), USDA

    Co-Investigator, Neuro-immune mediated control of mucosal immunity, Colin Reardon (Principal Investigator),

    Trainer, Post-baccalaureate research education program at UC Davis, Daniel Starr (Principal Investigator), NIH

    Most Recent 10 Publications

    • Melanie Gareau: Targeting the Microbiota, from Irritable Bowel Syndrome to Mood Disorders: Focus on Probiotics and Prebiotics 2018 Pusceddu MM, Murray K, Gareau MG Targeting the Microbiota, from Irritable Bowel Syndrome to Mood Disorders: Focus on Probiotics and Prebiotics Curr Pathobiol Rep,
    • Melanie Gareau: Human Evolutionary Loss of Epithelial Neu5Gc Expression may contribute to Species-specific Susceptibility to Cholera 2018 Alisson-Silva F, Liu J, Diaz S, Deng L, Gareau MG, Marchelletta R, Chen X, Nizet V, Varki N, Barrett KE, Varki A Human Evolutionary Loss of Epithelial Neu5Gc Expression may contribute to Species-specific Susceptibility to Cholera PLoS Pathogens,
    • Melanie Gareau: Intestinal Lactobacillus in health and disease, a driver or just along for the ride? 2018 Heeney DD, Gareau MG, Marco ML Intestinal Lactobacillus in health and disease, a driver or just along for the ride? Curr Opin Biotechnol,
    • Melanie Gareau: Neuroanatomy of the spleen: Mapping the relationship between sympathetic neurons and lymphocytes 2017 Murray K, Godinez DR, Brust-Mascher I, Miller EN, Gareau MG, Reardon C Neuroanatomy of the spleen: Mapping the relationship between sympathetic neurons and lymphocytes PloS one,
    • Melanie Gareau: Modulation of the microbiota-gut-brain axis by probiotics in a murine model of inflammatory bowel disease 2016 Emge JR, Huynh K, Miller EN, Kaur M, Reardon C, Barrett KE, Gareau MG Modulation of the microbiota-gut-brain axis by probiotics in a murine model of inflammatory bowel disease Am J Physiol Gastrointest Liver Physiol,
    • Melanie Gareau: TRPM8 on mucosal sensory nerves regulates colitogenic responses by innate immune cells via CGRP 2015 de Jong PR, Takahashi N, Peiris M, Bertin S, Lee J, Gareau MG, Paniagua A, Harris AR, Herdman DS, Corr M, Blackshaw LA, Raz E TRPM8 on mucosal sensory nerves regulates colitogenic responses by innate immune cells via CGRP Mucosal Immunol,
    • Melanie Gareau: High fat diet causes depletion of intestinal eosinophils associated with intestinal permeability. 2015 Johnson AM, Costanzo A, Gareau MG, Armando AM, Quehenberger O, Jameson JM, Olefsky JM High fat diet causes depletion of intestinal eosinophils associated with intestinal permeability. PloS one,
    • Melanie Gareau: Salmonella-induced diarrhea occurs in the absence of IL-8 receptor (CXCR2)-dependent neutrophilic inflammation. 2015 Marchelletta RR, Gareau MG, Okamoto S, Guiney DG, Barrett KE, Fierer J Salmonella-induced diarrhea occurs in the absence of IL-8 receptor (CXCR2)-dependent neutrophilic inflammation. J Infect Dis,
    • Melanie Gareau: Probiotics normalize the gut-brain-microbiota axis in immunodeficient mice 2014 Smith CJ, Emge JR, Berzins K, Lung L, Khamishon R, Shah P, Rodrigues DM, Sousa AJ, Reardon C, Sherman PM, Barrett KE, Gareau MG Probiotics normalize the gut-brain-microbiota axis in immunodeficient mice Am J Physiol Gastrointest Liver Physiol,
    • Melanie Gareau: Fluid and electrolyte secretion in the inflamed gut: novel targets for treatment of inflammation-induced diarrhea 2013 Gareau MG, Barrett KE Fluid and electrolyte secretion in the inflamed gut: novel targets for treatment of inflammation-induced diarrhea Current Opinion in Pharmacology,

    Most Recent 5 Book Chapters

    2018 Gareau MG, Reardon C, Barrett KE, Sherman PM: Impact of probiotics on communication between the brain-gut: Implications for the treatment of the psychological effects of digestive disease states, Colin Martin and Derek Larkin, (ed), Probiotics in Mental Health. 29-41.

    2016 Gareau MG: Gut Microbiome and Behavior; Cognition and the Microbiome, , International Review of Neurobiology. 227-246.

    2016 Huynh K, Schneider M, Gareau MG: Altering the gut microbiome for cognitive benefit, , The Gut Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota. 317-330.

    2014 Gareau MG: Chapter 16: Microbiota-gut-brain axis and cognitive function, Lyte M, Cryan JF, (ed), Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease. 357-71.

    External Links

    Lab Website