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  • Photo: Eleonora Napoli

    Eleonora Napoli- BS, PhD
    Associate Project Scientist
    Molecular Biosciences

    3011 VM3B
    Davis, CA 95616

    +1 530 752 1038
    enapoli@ucdavis.edu

       

    Research Focus

    My research focuses on the role of mitochondrial deficits in neurodegenerative diseases like Huntington's disease, FXTAS, and Friedreich's Ataxia, but also on the involvement of OXPHOS dysfunction in neurodevelopment disorders like autism.

    Specialty Focus

    Biochemistry

    Education

    2004 PhD Pharmacology and Toxicology, University of Padova, Padova Italy
    1998 BS Biological Sciences, University of Padova, Padova, Italy

    Active Research Grants

    Assistant Researcher, Midgut mitochondria function as a driver of resistance and fitness in Anopheline mosquitoes, Giulivi, Riehl, Luckhart (Principal Investigator), NIH

    Assistant Researcher, Genotype-Phenotype Relationships in Fragile X Families , Hagerman, R.J. (Principal Investigator), NIH

    Assistant Researcher, Harnessing midgut mitochondrial dynamics to enhance Anopheles mosquito fitness, Cecilia Giulivi (Principal Investigator), National Institute of Health (NIH)

    Collaborator, Environmental exposure unveils mitochondrial dysfunction in autism, Giulivi (Principal Investigator), Simons Foundation

    Most Recent 10 Publications

    • Eleonora Napoli: Toll-Like Receptor 4 Modulates Small Intestine Neuromuscular Function through Nitrergic and Purinergic Pathways 2017 Caputi V, Marsilio I, Cerantola S, Roozfarakh M, Lante I, Galuppini F, Rugge M, Napoli E, Giulivi C, Orso G, Giron MC. Toll-Like Receptor 4 Modulates Small Intestine Neuromuscular Function through Nitrergic and Purinergic Pathways Front Pharmacol,
    • Eleonora Napoli: Microbiota-activated PPAR-gamma signaling inhibits dysbiotic Enterobacteriaceae expansion 2017 Byndloss, M. X. Olsan, E. E. Rivera-Chavez, F. Tiffany, C. R. Cevallos, S. A. Lokken, K. L. Torres, T. P. Byndloss, A. J. Faber, F. Gao, Y. Litvak, Y. Lopez, C. A. Xu, G. Napoli, E. Giulivi, C. Tsolis, R. M. Revzin, A. Lebrilla, C. B. Baumler, A. J. Microbiota-activated PPAR-gamma signaling inhibits dysbiotic Enterobacteriaceae expansion Science,
    • Eleonora Napoli: Harnessing neural stem cells for treating psychiatric symptoms associated with fetal alcohol spectrum disorder and epilepsy 2017 Lippert T, Gelineau L, Napoli E, Borlongan CV. Harnessing neural stem cells for treating psychiatric symptoms associated with fetal alcohol spectrum disorder and epilepsy Prog Neuropsychopharmacol Biol Psychiatry,
    • Eleonora Napoli: Cell Therapy in Parkinson's Disease: Host Brain Repair Machinery Gets a Boost From Stem Cell Grafts 2017 Napoli, E. Borlongan, C. V. Cell Therapy in Parkinson's Disease: Host Brain Repair Machinery Gets a Boost From Stem Cell Grafts Stem Cells,
    • Eleonora Napoli: Stem Cell Recipes of Bone Marrow and Fish: Just What the Stroke Doctors Ordered 2017 Napoli, E., Borlongan, C. V. Stem Cell Recipes of Bone Marrow and Fish: Just What the Stroke Doctors Ordered Stem Cell Rev,
    • Eleonora Napoli: Plasma metabolic profile delineates roles for neurodegeneration, pro-inflammatory damage and mitochondrial dysfunction in the FMR1 premutation 2016 Giulivi, C. Napoli, E. Tassone, F. Halmai, J. Hagerman, R. Plasma metabolic profile delineates roles for neurodegeneration, pro-inflammatory damage and mitochondrial dysfunction in the FMR1 premutation Biochem J,
    • Eleonora Napoli: Plasma Biomarkers for Monitoring Brain Pathophysiology in FMR1 Premutation Carriers 2016 Giulivi C, Napoli E, Tassone F, Halmai J, Hagerman RJ Plasma Biomarkers for Monitoring Brain Pathophysiology in FMR1 Premutation Carriers Front Mol Neurosci,
    • Eleonora Napoli: Recent Advances in Stem Cell-Based Therapeutics for Stroke. 2016 Napoli E, Borlongan CV Recent Advances in Stem Cell-Based Therapeutics for Stroke. Transl Stroke Res,
    • Eleonora Napoli: Premutation in the Fragile X Mental Retardation 1 (FMR1) Gene Affects Maternal Zn-milk and Perinatal Brain Bioenergetics and Scaffolding. 2016 Napoli E, Ross-Inta C, Song G, Wong S, Hagerman R, Gane LW, Smilowitz JT, Tassone F, Giulivi C Premutation in the Fragile X Mental Retardation 1 (FMR1) Gene Affects Maternal Zn-milk and Perinatal Brain Bioenergetics and Scaffolding. Front Neurosci,
    • Eleonora Napoli: Altered redox mitochondrial biology in the neurodegenerative disorder fragile X-tremor/ataxia syndrome: use of antioxidants in precision medicine. 2016 Song G, Napoli E, Wong S, Hagerman R, Liu S, Tassone F, Giulivi C Altered redox mitochondrial biology in the neurodegenerative disorder fragile X-tremor/ataxia syndrome: use of antioxidants in precision medicine. Mol Med,