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    Damian C Genetos- BA, MS, PhD
    Associate Professor and Associate Professor in Residence and Associate Researcher
    Anatomy, Physiology & Cell Biology

    2207 Vet Med 3B
    Davis, CA 95616

    +1 530 754 0146
    dgenetos@ucdavis.edu

       

    Research Focus

    Bone cell mechanotransduction; cellular and molecular biology techniques

    Specialty Focus

    Cell biology

    Education

    1999 BA Physics, History, Indiana University, Bloomington, IN
    2002 MS Physiology, Indiana University, Bloomington, IN
    2005 PhD Physiology, Pennsylvania State University, Hershey, PA
    2007 Skeletal mechanotransduction, UC Davis School of Medicine, Department of Orthopaedic Surgery
    2010 Stem cells, UC Davis School of Veterinary Medicine, Veterinary Orthopaedic Research Lab

    Honors and Awards

    2011-2012 Collaborative Exchange Award, Orthopaedic Research Society
    2010 Academic Federation Research Travel Grant
    2009 Research award, 2009 Gordon Research Conference on Atherosclerosis, Tilton, NH
    2008-2011 NIH Individual National Research Service Award
    2002 Young Investigator Award, Fourth Bone Fluid Flow meeting, Amsterdam, The Netherlands
    2001-2004 NASA Pre-doctoral fellow

    Active Research Grants

    Principal Investigator, Integration of TGF-ß/ALK5 on Wnt signaling and mechanotransduction in bone, (Principal Investigator), NIH NIAMS

    Co-Investigator, Biomaterial Regulation of Cell Spheroids to Synergistically Enhance Bone Healing, J Kent Leach (Principal Investigator), NIH

    Most Recent 10 Publications

    • Damian C Genetos: Effect of alendronate on post-traumatic osteoarthritis induced by anterior cruciate ligament rupture in mice 2015 Khorasani MS, Diko S, Hsia AW, Anderson MJ, Genetos DC, Haudenschild DR, Christiansen BA Effect of alendronate on post-traumatic osteoarthritis induced by anterior cruciate ligament rupture in mice Arthritis Res Ther,
    • Damian C Genetos: Parathyroid hormone regulation of hypoxia-inducible factor signaling in osteoblastic cells 2015 Wong A, Loots GG, Yellowley CE, Dose AC, Genetos DC Parathyroid hormone regulation of hypoxia-inducible factor signaling in osteoblastic cells Bone,
    • Damian C Genetos: Altered bone development in a mouse model of peripheral sensory nerve inactivation 2014 Heffner MA, Anderson MJ, Yeh GC, Genetos DC, Christiansen BC Altered bone development in a mouse model of peripheral sensory nerve inactivation Journal of Musculoskeletal and Neuronal Interaction,
    • Damian C Genetos: Nanocomposite scaffold for chondrocyte growth and cartilage tissue engineering: Effects of Carbon nanotube surface functionalization 2014 Chahine NO, Collette NM, Thomas CB, Genetos DC, Loots GG Nanocomposite scaffold for chondrocyte growth and cartilage tissue engineering: Effects of Carbon nanotube surface functionalization Tissue Engineering,
    • Damian C Genetos: Lysophosphatidic acid protects human mesenchymal stromal cells from differentiation-dependent vulnerability to apoptosis 2014 Binder BY, Genetos DC, Leach JK Lysophosphatidic acid protects human mesenchymal stromal cells from differentiation-dependent vulnerability to apoptosis Tissue Engineering,
    • Damian C Genetos: Impaired osteoblast differentiation in Annexin A2- and -A5-deficient cells 2014 Genetos DC, Wong A, Weber TJ, Karin NJ, Yellowley CE Impaired osteoblast differentiation in Annexin A2- and -A5-deficient cells PLoS ONE,
    • Damian C Genetos: Genomic approaches in breast cancer research 2013 Donahue HJ, Genetos DC Genomic approaches in breast cancer research Briefings in Functional Genomics,
    • Damian C Genetos: Age-related changes in gap junctional intercellular communication in osteoblastic cells 2012 Genetos DC, Zhou Z, Li Z, Donahue HJ Age-related changes in gap junctional intercellular communication in osteoblastic cells J Orthop Res,
    • Damian C Genetos: Long-term administration of AMD3100, an antagonist of SDF-1/CXCR4 signaling, alters fracture repair 2012 Toupadakis CA, Wong A, Genetos DC, Chung DJ, Murugesh D, Anderson MJ, Loots GG, Christiansen BA, Kapatkin AS, Yellowley CE Long-term administration of AMD3100, an antagonist of SDF-1/CXCR4 signaling, alters fracture repair J Orthop Res,
    • Damian C Genetos: Targeted Deletion of Sost Distal Enhancer Increases Bone Formation and Bone Mass 2012 Collette NM, Genetos DC, Economides AN, Xie L, Shahnazari M, Yao W, Lane NE, Harland RM, Loots GG Targeted Deletion of Sost Distal Enhancer Increases Bone Formation and Bone Mass Proc Natl Acad Sci USA,

    Most Recent 5 Book Chapters

    2014 Donahue HJ, Duncan RL, Genetos DC: Channel activation and mechanotransduction, Neu C and Genin G, (ed), CRC Handbook of Imaging in Biological Mechanics. 433-442.

    2012 Genetos DC, Jacobs CR: Bone cell mechanoresponsiveness, X.E. Guo and M.R. Silva, (ed), Skeletal Aging and Osteoporosis: Biomechanics and Mechanobiology. 177-90.

    2005 Duncan RL, Genetos DC: Calcium signaling in osteoblasts in response to mechanical stimulation, R. Aaron and M. Bolander, (ed), Physical Regulation of Skeletal Repair, Rosemont, IL. .