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  • Photo: Kevork Hagopian

    Kevork Hagopian- Baccalaureate, BSc, PhD
    Project Scientist
    Molecular Biosciences

    3017 VM3B
    Davis, CA 95616

    +1 530 752 3758
    khagopian@ucdavis.edu

       

    Research Focus

    Influence of aging, caloric restriction, nutritional and genetic manipulations on metabolic pathways. The role mitochondria play in the aging process and the effects of the above mentioned interventions on various mitochondrial functions. Oxidative stress and free radical generation during the aging process and under various dietary manipulation and the role mitochondria play in the process.

    Specialty Focus

    Biochemistry

    Education

    1970 Baccalaureate , Armenian Private School, Basra, Iraq
    1974 BSc Biology, University of Basra, Iraq
    1985 PhD Biochemistry, University College Dublin, Ireland

    Honors and Awards

    1983 & 1984 Boghos Nubar Pacha Foundation (Belgium) Scholarship for postgraduate studies in Dublin Ireland
    1979 Gulbenkian Foundation (Portugal) Scholarship for postgraduate studies in Dublin, Ireland

    Active Research Grants

    Principal Investigator, Shc, mitochondria, healthy aging and longevity, Ramsey JJ (Principal Investigator), National Institue of Health (NIH)

    Most Recent 10 Publications

    • Kevork Hagopian: Shc depletion stimulates brown fat activity in vivo and in vitro 2014 Tomilov A, Bettaieb A, Kim K, Sahdeo S, Tomilova N, Lam A, Hagopian K, Connell M, Fong J, Rowland D, Griffey S, Ramsey JJ, Haj F, Cortopassi G Shc depletion stimulates brown fat activity in vivo and in vitro Aging Cell,
    • Kevork Hagopian: The influence of dietary lipid composition on skeletal muscle mitochondria from mice following eight months of calorie restriction 2014 Chen Y, Hagopian K, Bibus D, Villalba JM, López-Lluch G, Navas P, Kim K, Ramsey JJ The influence of dietary lipid composition on skeletal muscle mitochondria from mice following eight months of calorie restriction Physiol Res,
    • Kevork Hagopian: The Influence of Shc Proteins on Life Span in Mice 2014 Ramsey JJ, Tran D, Giorgio M, Griffey SM, Koehne A, Laing ST, Taylor SL, Kim K, Cortopassi GA, Lloyd KC, Hagopian K, Tomilov AA, Migliaccio E, Pelicci PG, McDonald RB The Influence of Shc Proteins on Life Span in Mice J Gerontol A Biol Sci Med Sci,
    • Kevork Hagopian: Calorie restriction influences key metabolic enzyme activities and markers of oxidative damage in distinct mouse liver mitochondrial sub-populations 2013 Hagopian K, Soo Hoo R, López-Domínguez JA, Ramsey JJ Calorie restriction influences key metabolic enzyme activities and markers of oxidative damage in distinct mouse liver mitochondrial sub-populations Life Sci,
    • Kevork Hagopian: The influence of dietary lipid composition on liver mitochondria from mice following 1 month of calorie restriction 2013 Chen Y, Hagopian K, Bibus D, Villalba JM, López-Lluch G, Navas P, Kim K, McDonald RB, Ramsey JJ The influence of dietary lipid composition on liver mitochondria from mice following 1 month of calorie restriction Biosci Rep,
    • Kevork Hagopian: Shc proteins influence the activities of enzymes involved in fatty acid oxidation and ketogenesis 2012 Hagopian K, Tomilov AA, Tomilova N, Kim K, Taylor SL, Lam AK, Cortopassi GA, McDonald RB, Ramsey JJ Shc proteins influence the activities of enzymes involved in fatty acid oxidation and ketogenesis Metabolism,
    • Kevork Hagopian: The influence of dietary lipid composition on skeletal muscle mitochondria from mice following 1 month of calorie restriction 2012 Chen Y, Hagopian K, McDonald RB, Bibus D, López-Lluch G, Villalba JM, Navas P, Ramsey JJ The influence of dietary lipid composition on skeletal muscle mitochondria from mice following 1 month of calorie restriction J Gerontol A Biol Sci Med Sci,
    • Kevork Hagopian: The p66Shc knocked out mice are short lived under natural conditions 2012 Giorgio M, Berry A, Berniakovich I, Poletaeva I, Trinei M, Stendardo M, Hagopian K, Ramsey JJ, Cortopassi GA, Migliaccio E, Notzli S., Amrein I, Lipp HP, Cirulli F, Pelicci P-G The p66Shc knocked out mice are short lived under natural conditions Aging Cell,
    • Kevork Hagopian: Caloric restriction influences hydrogen peroxide generation in mitochondrial sub-populations from mouse liver 2011 Hagopian K, Chen Y, Simmons Domer, K, Soo Hoo R, Bentley T, McDonald RB, Ramsey JJ Caloric restriction influences hydrogen peroxide generation in mitochondrial sub-populations from mouse liver J Bioenerg Biomembr,
    • Kevork Hagopian: The Shc locus regulates insulin signaling and adiposity in mammals. 2011 Tomilov AA, Ramsey JJ, Hagopian K, Giorgio M, Kim KM, Lam A, Migliaccio E, Lloyd KC, Berniakovich I, Prolla TA, Pelicci P, Cortopassi GA The Shc locus regulates insulin signaling and adiposity in mammals. Aging Cell,

    Most Recent 5 Book Chapters

    2007 Ramsey JJ, Hagopian K: Bioenergenetics, , Encyclopedia of Gerontology: Age, Aging and the Aged. Second Edition, Oxford, UK. 170-177.