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  • Photo: Leslie Lyons

    Leslie Lyons- BS, MS, PhD
    Professor Emeritus
    Population Health & Reproduction

    260 CCAH
    Davis, CA 95616

    +1 530 754 5546
    lalyons@ucdavis.edu

       

    Specialty Focus

    Genetics

    Education

    1996 Post-Doctoral Fellow Feline Genetics, Laboratory of Viral Carcinogenesis, National Cancer Institute, Frederick, MD
    1992 Post-Doctoral Fellow Human Genetics, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA
    1991 PhD Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA
    1987 MS Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA
    1985 BS Biochemistry, University of Pittsburgh, College of Arts and Sciences, Pittsburgh, PA

    Honors and Awards

    2010 AVMF / Winn Feline Foundation Research Award
    2008 Chancellor's Research Award, nominated
    2007 Chancellor's Research Award, nominated
    2001 Undergraduate mentoring award, nominated
    1990-1991 Doctoral Student Organization, GSPH
    1987-1991 Graduate Student Representative, GSPH
    1982 Phi Eta Sigma, University of Pittsburgh

    Licenses

    Short Course on Medical and Experimental Mammalian Genetics, Jackson Laboratory, Bar Harbor, ME July (2 weeks)
    Feline Genetics and Health for Cat Breeders, Cornell University
    American Association of Laboratory Animal Science (AALAS) Laboratory Animal Technician
    Advanced Linkage Analysis, Columbia University

    Active Research Grants

    Principal Investigator, Development of Viable Tissue Cultures for Californian Bats (Order Chiroptera), Project No. 2000147, (Principal Investigator), Genetic Resources Conservation Program

    Co-Principal Investigator, Molecular investigation of melanocyte migration in white spotted cats, Barbara Gandolfi (Principal Investigator), Winn Feline Foundation

    Co-Investigator, Analysis of Genes Influencing PKD Progression in Cats, Robert Grahn (Principal Investigator), UCD: VM: Center for Companion Animal Health

    Principal Investigator, Genetic Mapping Resources for Common Mammalian Diseases, (Principal Investigator), NIH: National Center Research Resources

    Principal Investigator, Mammalian Models for Human Disease, (Principal Investigator), UC Davis CCAH Match NIH R24

    Co-Investigator, Health Concerns of Dominant Traits in Domestic Cats, Robert Grahn (Principal Investigator), Winn Feline Foundation

    Principal Investigator, Genetic Components Influencing the Feline – Human Social Bond, Leslie A. Lyons (Principal Investigator), NIH - NICHD

    Co-Principal Investigator, Conclusion of the Orange Saga, Robert Grahn (Principal Investigator), UCD: VM: Center for Companion Animal Health

    Co-Investigator, MITF - The Great White Hope, Barbara Gandolfi (Principal Investigator), UCD: VM: Center for Companion Animal Health

    Principal Investigator, Genome-wide Association Studies of Brachycephaly in Domestic Cats (96 DNA arrays = $21,600), Leslie Lyons (Principal Investigator), Cat Health Network / Morris Animal Foundation

    Principal Investigator, CHN - UC Davis CCAH GWAS Match $25.00 per array, Leslie Lyons (Principal Investigator), UC Davis CCAH

    Principal Investigator, Genetic Estimation of Introgression between Domestic Cat (276 DNA arrays = $62,100) and Wildcat Populations, (Principal Investigator), Cat Health Network / Morris Animal Foundation

    Co-Principal Investigator, Genome-wide Association Study for Congenital Muscular Dystrophy in Sphynx and Devon Rex cats (60 DNA arrays = $13,500), Robert Grahn (Principal Investigator), Cat Health Network

    Co-Investigator, Genetic susceptibility to Feline Infectious Peritonitis (FIP), Niels Pedersen (Principal Investigator), Cat Health Network / Morris Animal Foundation

    Co-Investigator, Osteochondrodysplasia in the Scottish Fold cat breed (200 DNA arrays, $45,000), Bianca Haase (Principal Investigator), Cat Health Network / Morris Animal Foundation

    Co-Principal Investigator, Identification of the Gene Causing Autosomal Dominant Feline Dwarfism, Robert Grahn (Principal Investigator), UCD VM: Center for Companion Animal Health

    Co-Principal Investigator, Molecular Characterization of Bengal Progressive Retinal Atrophy, Robert Grahn (Principal Investigator), Winn Feline Foundation & CCAH Match $4,221

    Co-Principal Investigator, Characterization of the AB blood type in the domestic cat, Gandolfi, Barbara (Principal Investigator), UC Davis CCAH

    Most Recent 10 Publications

    • Leslie Lyons: Extent of linkage disequilibrium in the domestic cat, Felis silvestris catus, and its breeds. 2013 Alhaddad, H, Khan, R, Grahn, RA, Gandolfi, B, Mullikin, JC, Cole, SA, Gruffydd-Jones, TJ, Häggström, J, Lohi, H, Longeri, M, Lyons, LA Extent of linkage disequilibrium in the domestic cat, Felis silvestris catus, and its breeds. PloS one,
    • Leslie Lyons: Developmental validation of Mini-DogFiler for degraded canine DNA. 2013 Kun, T, Lyons, LA, Sacks, BN, Ballard, RE, Lindquist, C, Wictum, EJ Developmental validation of Mini-DogFiler for degraded canine DNA. Forensic science international. Genetics,
    • Leslie Lyons: Myosin-Binding Protein C DNA Variants in Domestic Cats (A31P, A74T, R820W) and their Association with Hypertrophic Cardiomyopathy 2013 Longeri, M., Ferrari, P., Knafelz, P., Mezzelani, A., Marabotti, A., Milanesi, L., Pertica, G., Polli, M., Brambilla, P. G., Kittleson, M., Lyons, L. A., Porciello, F. Myosin-Binding Protein C DNA Variants in Domestic Cats (A31P, A74T, R820W) and their Association with Hypertrophic Cardiomyopathy J Vet Intern Med,
    • Leslie Lyons: Enhancing genotyping of MAOA-LPR and 5-HTT-LPR in rhesus macaques (Macaca mulatta) 2012 Karere, G. M. Sullivan, E. Kinnally, E. L. Capitanio, J. P. Lyons, L. A. Enhancing genotyping of MAOA-LPR and 5-HTT-LPR in rhesus macaques (Macaca mulatta) Journal of medical primatology,
    • Leslie Lyons: Comparative fertility of freshly collected vs frozen-thawed semen with laparoscopic oviductal artificial insemination in domestic cats 2012 Lambo, C. A., Grahn, R. A., Lyons, L. A., Bateman, Hl, Newsom, J., Swanson, W. F. Comparative fertility of freshly collected vs frozen-thawed semen with laparoscopic oviductal artificial insemination in domestic cats Reprod Domest Anim,
    • Leslie Lyons: Genetic testing in domestic cats. 2012 Lyons, LA Genetic testing in domestic cats. Molecular and cellular probes,
    • Leslie Lyons: First WNK4-hypokalemia animal model identified by genome-wide association in Burmese cats. 2012 Gandolfi, B, Gruffydd-Jones, TJ, Malik, R, Cortes, A, Jones, BR, Helps, CR, Prinzenberg, EM, Erhardt, G, Lyons, LA First WNK4-hypokalemia animal model identified by genome-wide association in Burmese cats. PloS one,
    • Leslie Lyons: A novel CYP27B1 mutation causes a feline vitamin D-dependent rickets type IA. 2012 Grahn, RA, Ellis, MR, Grahn, JC, Lyons, LA A novel CYP27B1 mutation causes a feline vitamin D-dependent rickets type IA. Journal of feline medicine and surgery,
    • Leslie Lyons: Erythrocyte pyruvate kinase deficiency mutation identified in multiple breeds of domestic cats. 2012 Grahn, RA, Grahn, JC, Penedo, MC, Helps, CR, Lyons, LA Erythrocyte pyruvate kinase deficiency mutation identified in multiple breeds of domestic cats. BMC veterinary research,
    • Leslie Lyons: Enhancing genotyping of MAOA-LPR and 5-HTT-LPR in rhesus macaques (Macaca mulatta). 2012 Karere, GM, Sullivan, E, Kinnally, EL, Capitanio, JP, Lyons, LA Enhancing genotyping of MAOA-LPR and 5-HTT-LPR in rhesus macaques (Macaca mulatta). Journal of medical primatology,

    Most Recent 5 Book Chapters

    2011 Lyons LA: Genetics of Feline Diseases and Traits, Susan Little, (ed), The Cat: Clinical Medicine and Management. .

    2011 Lyons LA: The Feline Genome and Clinical Implications, Susan Little, (ed), The Cat: Clinical Medicine and Management. .

    2011 Lyons LA, Kurushima JD: A Short Natural History of the Cat and Its Relationship with Humans, Susan Little, (ed), The Cat: Clinical Medicine and Management. .

    2009 Bighignoli B, Owens SD, Froenicke F, Lyons LA: Blood types of the domestic cat, August J, (ed), Consultations in Feline Medicine. .

    2009 Lyons LA: Genetic testing in domestic cats, August J, (ed), Consultations in Feline Medicine. .